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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63369 | CXCR4 antagonist 4 | ||
CXCR4 antagonist 4 is an orally active and potent CXCR4 antagonist with an IC50 of 24 nM. CXCR4 antagonist 4 inhibits CYP 2D6 activity, increases PAMPA permeability, and effectively blocks entry of human immunodeficiency... | |||
T39742 | CXCR4 antagonist 2 | ||
CXCR4 antagonist 2 is a CXCR4 antagonist with an IC 50 value of 47 nM. | |||
T40786 | CXCR4 antagonist 1 | CXCR4 antagonist 1 | |
CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity. | |||
TQ0174 | Mavorixafor | AMD-070 | CXCR |
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC... | |||
T14665 | Motixafortide | BL-8040,BKT140 (4-fluorobenzoyl),TF14016 | CXCR |
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). | |||
T10296 | Mavorixafor trihydrochloride | AMD-070 trihydrochloride | HIV Protease |
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (I... | |||
T14670 | BMS-1166 hydrochloride | Others | |
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immun... | |||
T69081 | KRH-1636 | ||
KRH-1636 is an orally active, selective and extremely potent CXC chemokine receptor 4 antagonist. KRH-1636 exhibits a potent and selective anti-HIV-1 activity. KRH-1636 efficiently blocked replication of various T cell ... | |||
T83763 | EPI-X4 TFA | Endogenous Peptide Inhibitor of CXCR4 | |
EPI-X4, an endogenous peptide fragment of human serum albumin (amino acids 408-423), serves as an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4). It effectively prevents calcium mobilization and receptor in... | |||
T83769 | TC 14012 hydrochloride | H-Arg-Arg-Nal-Cys-Tyr-Cit-Lys-D-Cit-Pro-Tyr-Arg-Cit-Cys-Arg-NH2 | |
TC 14012, a peptidomimetic compound, acts as both an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4; IC50 = 2.9 nM) and as an agonist for CXCR7, effectively recruiting β-arrestin in HEK293T cells that expres... |